Changing lives

with first-in-class 

gene therapies for
ALS and FTD

We pioneer genetic medicines that directly target
the root causes of neurodegenerative disease.

What sets us apart

A clear path from science to impact

Our lead program: 
CTX1000

Celosia’s lead program is a first-in-class gene therapy targeting toxic 
TDP-43 in ALS and FTD, currently in IND submission with first-in-patient 
dosing expected in Q3 2025.

What is TDP-43?

TDP-43 is a protein that helps keep nerve cells healthy, but in ALS and FTD it ends up in the wrong place, becomes toxic, and damages those cells.

Other programs

Celosia is advancing additional programs in ALS (CTX2000), Alzheimer’s disease (CTX3000), and epilepsy syndromes (CTX4000).

Our pipeline

Celosia's pipeline infographic

Meet our team

Dr Kathryn Sunn

PhD, CEO

Yazi Diana Ke

PhD, Inventor / Chief Operating Officer

Professor Lars M Ittner

MD, Founder / Chief Scientific and
Medical Officer